The ParSe algorithm – predict phase-separating protein regions from the primary sequence.

ParSe source code on GitHub

ParSe web-app at GitHub

ParSe web-app at folding.chemistry.msstate

 

ParSe v2 – a second-generation version of ParSe.

ParSe_v2 source code on GitHub

ParSe_v2 web-app on GitHub

 

Analyze large sequence sets using ParSe v2

ParSe_v2_FASTA web-app on GitHub

 

Predict phase separation potentials for a sequence set

ParSe_v2_potentials web-app on GitHub

 

IDP hydrodynamic size

Predict hydrodynamic radius, R_h, of an intrinsically disordered protein (IDP) from its primary sequence.

 

Curated datasets of ID, PS ID, and folded protein sequences, used to develop ParSe v2 (as described in Ibrahim et al, JBC 2023)
IDR sequences
PS IDR sequences
folded sequences

 

Python scripts that download from UniProt a user-defined FASTA file
Script that downloads one sequence per UniProtKB accession ID
Script that downloads canonical sequence plus splice variants